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P. Maheshwari ¹, D. Pavithra ¹, T. T. Neethu ¹, T. S. Shanmugarajan ¹, P. Shanmugasundaram ¹

Affiliations
1 Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai-600117, Tamil Nadu, IN

Abstract

Aim and Objectives: The main aim of the study is to compare the levels of anxiety and depression, psychological distress between persons with diabetes with a history of foot ulcer, persons without history of foot ulcer and persons without diabetes. Materials and Methods: This study which includes prospective study. The study was done in a five different general medicine department and were carried out for a period of 6 months on both in-patient and out-patients in general medicine department. Chi-square is used to differeniate the incidence of anxiey and depression between patients with diabetic foot ulcer and diabetes without foot ulcer. Result and Discussion: A total of 90 patients were screened. Out of selected 90 patients, the age of 20-29 years 5(6%) were males and females, in the age of 30-39 years 14(15%), in the age of 40-49 years 24(27%), in the age of above 50-59 years 45(50%) and in the age of 60 years 2(2%%) were found. Conclusion: In this study the Abnormal anxiety and depression levels are more in diabetic foot ulcer when compared to those with diabetes.There was significant association found between diabetes, diabetic foot ulcer and psychological distress.

Keywords

Hads-A, Hads-D.

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Mohamed Zerein Fathima ¹, T. S. Shanmugarajan ¹, I. Somasundharam ¹, J. Anisha Ebens ¹, T. T. Neethu ¹

Affiliations
1 Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels University (VISTAS), Pallavaram-600117, Tamilnandu, IN

Abstract

Trichosanthes cucumerina linn is used as a traditional medicine for various diseases. In the present study was conducted to evaluate theanalgesic activity for Petroleum ether and Methanol extract of Trichosanthes cucumerinalinn and the activity was compared with diclofenac sodium as a standardand assessed using acetic acid induced abdominal writhing in mice.The methanolic extract exhibited significant value (P<0.001)analgesic activity as evidenced by increased the percentage of reduction in reaction time. The results thus support the Trichosanthes cucumerina linn used as ananalgesic agent. The plant showed no sign of toxicityup to the dose of 100 mg/kg in mice.

Keywords

Trichosanthes cucumerina linn, Analgesic Activity, Phytochemical Screening, Structural Elucidation, IR.

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